S.I.U. School of Medicine
801 N. Rutledge St. Room 4389
P.O. Box 19628
Springfield IL 62794-9628
Office: (217) 545-7962
Lab: (217) 545-7979
Magister (equivalent MS) 1962 Jagiellonian University, Krakow, Poland Biology (Zoology)
PhD 1965 University of Kansas Zoology (Genetics)
Aging, longevity genes, growth hormone, insulin, mice, caloric restriction
We are working on the genetic control of aging in mammals and on endocrine mechanisms responsible for the effects of longevity genes
Al-Regaiey KA, Masternak MM, Bonkowski M, Sun L, Bartke A. Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor 1/insulin signaling and caloric restriction. Endocrinology 146:851-860, 2005.
Bonkowski MS, Rocha JS, Masternak MM, Al-Regaiey KA, Bartke A. Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. Proceedings of the National Academy of Sciences 103:7901-7905, 2006.