Department of Molecular, Cellular & Systemic Physiology Graduate
PHSL 420a,b-6 (3,3) Principles of Pharmacology. Examines basic principles of pharmacology (pharmacokinetics) and the action of various classes of drugs on living organisms. Drug classes covered include those affecting most organ systems of the human body, such as the nervous, cardiovascular, gastrointestinal and renal systems as well as drugs used for antibiotic and cancer chemotherapy. Three lectures per week. Prerequisites: Chem. 340 and 342 (or equivalent), PHSL 310 or 410.
PHSL 430-3 Cellular and Molecular Physiology. This course will examine the molecular and cellular aspects of physiology, with special emphasis on the experiments used to examine the regulation of gene expression, protein activities, and cellular functions in eukaryotes. Topics include: mechanisms regulating gene expression, signaling pathways, cancer biology, and the use of experimental model organisms. Required of Physiology majors. Prerequisite: BIOL 200 A & B or CHEM 350 & 351.
PHSL 460-2 Electron Microscopy. Lecture course designed to introduce the student to the theory and principles of electron microscopy. Two lecture hours per week. Prerequisite: senior standing or permission of instructor.
PHSL 470-3 Biological Clocks. Study of the temporal aspects of diverse physiological and behavioral functions which possess diurnal and sectional periodicity. Species covered will include many eukaryotic organisms including plants, but will mainly stress mammals. Oscillations in sleep-wake cycle, locomotion, reproduction, hormonal secretion and numerous other processes will be explored. In addition, the effects of biological clocks in humans and the effect of jet lag and depression will be examined. Prerequisite: 310.
PHSL 570 Advanced Physiological Topics: (3 credits) Studies of current research and literature in various topic areas, including neuroscience.
PHSL 573-3 Neuroanatomy. A detailed survey of human neuroanatomy. The course will include radiographic, cross sectional and developmental anatomy of the nervous system. Dissection of the human brain will occur in general laboratory sessions. Three lectures per week.
PHSL 574-3 Neuropharmacology. (Same as Pharmacology 574.) A detailed examination of the biochemical aspects of neuropharmacology with emphasis on neurotransmitters—their synthesis, storage, release and metabolism in the central and peripheral nervous system. Considerable emphasis is placed on major research developments (both past and present) that influence how one studies the action of drugs on the nervous system. Prerequisite: 410, and Chemistry 450, or equivalent.
PHSL 575 Neuroendocrinology: (3 Credits) Designed to investigate and discuss the current research and historical aspects of the field of neuroendocrinology. In addition, designed to have students examine and evaluate current literature in the field and through discussion have them present their analysis of the research. One hour of lecture, one hour of discussion of textual material, one hour of multiple reports on library research. Prerequisite: 410a, b or equivalent, or an undergraduate/graduate endocrinology course, or consent of instructor.
PHSL 590 Readings or Research in Current Physiological Topics: (1-4 credits) By special arrangement with instructor with whom student wishes to work. Graded S/U only.